These include:. For these conditions, the risk of serious side effects caused by Cipro and Levaquin outweigh their benefits. Because of these serious side effects, Cipro and Levaquin are often not considered first-choice antibiotics. Cipro and Levaquin are both brand-name drugs. The generic name of Levaquin is levofloxacin.
Brand-name Levaquin is usually more expensive than brand-name Cipro. The generic forms of Cipro and Levaquin cost about the same. Cipro and Keflex cephalexin are both antibiotics, but they belong to different drug classes. Keflex is a cephalosporin antibiotic. Cipro and Keflex are both FDA-approved to treat some similar infections. Cipro and Keflex are both effective for their FDA-approved uses.
The FDA has recommended that Cipro and other fluoroquinolone antibiotics not be used as a first-choice antibiotic for certain infections. For these conditions, the risk of serious side effects caused by Cipro outweigh its benefits. Cipro and Keflex have some similar common and serious side effects. Examples of these side effects are included below. Cipro and Keflex are both brand-name drugs. The generic name of Keflex is cephalexin. Brand-name Keflex is usually more expensive than brand-name Cipro.
The generic forms of Cipro and Keflex cost about the same. In most cases, Cipro treatment is short term, from 3 to 14 days. But for some infections, such as certain bone or joint infections, treatment may last several weeks. Cipro does not usually cause you to feel tired, but in some cases, people report feeling tired while taking it. Feeling more tired than usual may be due to your condition rather than the medication.
But if your symptoms are severe, call or go to the nearest emergency room right away. Cipro is sometimes prescribed by veterinarians to treat infections in dogs and cats. If you think your dog or cat has an infection, see your veterinarian for an evaluation and treatment. Cipro and other fluoroquinolone antibiotics can cause a falsely positive result for opioids on urine drug screenings.
Before taking Cipro, talk with your doctor about your health history. Cipro may not be appropriate for you if you have certain medical conditions. For people with diabetes : Cipro and other fluoroquinolones can sometimes cause severe low blood sugar.
This is more likely to happen in those with diabetes who are taking hypoglycemic drugs. You may need to monitor your blood sugar levels more closely if you take Cipro.
For people with myasthenia gravis : Cipro and other fluoroquinolone antibiotics can worsen muscle weakness in people with this condition. If you have myasthenia gravis, you should not take Cipro.
For people with QT interval prolongation : People with QT interval prolongation have a higher risk of having a potentially serious irregular heartbeat. Taking Cipro might worsen this condition, resulting in a life-threatening arrhythmia. Sun exposure : Cipro can make your skin more sensitive to sunlight. You may be more likely to get a severe sunburn while taking Cipro.
When Cipro is dispensed from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically one year from the date the medication was dispensed. Oral suspensions often have a much earlier expiration date. The purpose of such expiration dates is to guarantee the effectiveness of the medication during this time. However, an FDA study showed that many medications may still be good beyond the expiration date listed on the bottle.
How long a medication remains good can depend on many factors, including how and where the medication is stored. Cipro should be stored at room temperature in its original container. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.
Cipro is a fluoroquinolone antibiotic that has bactericidal effects through inhibition of bacteria DNA gyrase and topoisomerase IV. These enzymes are required for bacterial DNA replication, transcription, repair, and recombination. The bioavailability of Cipro is about 70 percent when taken orally. Maximum blood concentrations occur within one to two hours. Food delays Cipro tablet absorption, resulting in peak levels occurring closer to two hours, but does not delay absorption of Cipro suspension.
However, food does not change overall absorption and peak levels of Cipro tablet or suspension. About 40 percent to 50 percent of Cipro is excreted in the urine unchanged.
Urinary excretion of Cipro is complete within about 24 hours after dosing. The half-life of Cipro about four to five hours for adults and children.
In people with reduced kidney function, it may increase to six to nine hours. Cipro is contraindicated in people with a history of hypersensitivity to Cipro or to any other fluoroquinolone antibiotic. Concomitant administration with tizanidine is also contraindicated due to potentiation of sedative and hypotensive effects of tizanidine. Reconstituted Cipro suspension should also be stored at room temperature for up to 14 days.
The suspension should not be frozen. Disclaimer : MedicalNewsToday has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Suspension and tablet are not bioequivalent on a mg-to-mg basis.
Adults and Adolescents Age 13 years and older Pneumonia, community-acquired - mg twice a day for 10 days PI Sinusitis - mg twice a day or mg once daily for 10 days IDSA Skin infections - mg twice a day for 10 days PI Strep throat - mg twice a day for 5 - 10 days or mg once daily for 10 days PI Urinary tract infection - mg twice a day for 3 - 7 days IDSA. Cefdinir is a third generation cephalosporin May take without regard to food Iron supplements and antacids reduce cefdinir absorption.
Do not take within 2 hours of each other. Adults and Adolescents Age 12 years and older Pneumonia, community-acquired - mg twice a day for 14 days PI Skin infections - mg twice a day for 10 days PI Strep throat - mg twice a day for 10 days PI.
Cefditoren has been discontinued in the U. Cefditoren is a third generation cephalosporin Take with a meal to increase absorption Drugs that reduce gastric acidity e.
Give with clindamycin. See AAP sinusitis recs. Cefpodoxime is a third generation cephalosporin Suspension may be taken without regard to food Tablets should be taken with food Drugs that reduce gastric acidity e.
Adolescents and Adults age 12 years and older Otitis media - mg once daily for 10 days PI Strep throat - mg once daily for 10 days PI. Ceftibuten is a third generation cephalosporin Ceftibuten should be taken at least 2 hours before or one hour after a meal.
Food decreases absorption. Pediatric E. Topical See topical derm chart. May take without regard to food Liver disease - dose adjustment not likely necessary Kidney disease - no dose adjustment necessary. May take without regard to food Mix packet with 3 - 4 ounces of water Kidney disease - clearance is decreased. Manufacturer makes no specific recommendation. Adults 18 years and older Pneumonia, community-acquired - mg every 12 hours for 5 days PI.
Take at least 1 hour before a meal or 2 hours after a meal. Strong and moderate CYP3A4 inducers may decrease the effectiveness of lefamulin. Do not take lefamulin with strong CYP3A4 inhibitors. Monitor for adverse effects when taking with moderate CYP3A4 inhibitors. Lefamulin is a P-glycoprotein substrate. P-glycoprotein inducers may decrease the effectiveness of lefamulin.
Do not take with strong P-glycoprotein inhibitors. Monitor for adverse effects when taking with moderate P-glycoprotein inhibitors. Lefamulin can prolong the QT interval. Avoid use in patients with prolonged QT syndrome and in those taking concomitant medications that can prolong the QT interval. Not recommended. Kidney disease - no dose adjustment necessary. Do not take within 2 weeks of other MAO inhibitors.
It is a first-generation cephalosporin antibiotic, which belongs under the larger classification of beta-lactam antibiotics. Cephalexin interferes with cell wall synthesis by binding penicillin-binding proteins inside the cellular wall.
Ultimately, when cephalexin is dosed appropriately, it causes lysis, or destruction, or the bacterial cell. Different bacterial types contain different bacterial binding proteins, so the effectiveness of cephalexin varies with different types of bacteria. Cephalexin is available as an oral tablet or capsule, as well as an oral suspension. The brand name of cephalexin is Keflex. It is used by infants, children, and adults. Amoxicillin is a prescription medication also used to treat a variety of bacterial infections.
It is a penicillin antibiotic but also falls under the larger classification of beta-lactam antibiotics. Amoxicillin, like cephalexin, interferes with cell wall synthesis by binding penicillin-binding proteins inside the cellular wall leading the destruction of the bacterial cell. Amoxicillin is available as an oral tablet or capsule, chewable tablet, as well as an oral suspension. The brand name of amoxicillin is Amoxil or Polymox.
Sign up for Amoxicillin price alerts and find out when the price changes! Get Price Alerts. Cephalexin has been shown to be active against a variety of bacterial organisms including Escherichia coli , Haemophilus influenzae beta-lactamase negative , Klebsiella pneumoniae , Moraxella catarrhalis , Proteus mirabilis , Staphylococcus aureus MSSA , Staphylococcus epidermidis , Streptococcus pneumoniae , and Streptococcus pyogenes.
The sensitivity of these organisms allows cephalexin to also be effective in treating many common types of infections including upper respiratory infections such as sinusitis , pharyngitis, and tonsillitis.
Amoxicillin is also effective against lower respiratory infections such as community-acquired pneumonia. Other uses of cephalexin include skin infections cellulitis , bone and joint infections, otitis media, and urinary tract infections UTI. Amoxicillin has been shown to be active against a variety of bacterial organisms including Enterococcus faecalis , Escherichia coli , Haemophilus influenzae beta-lactamase negative , Helicobacter pylori , Proteus mirabilis , Staphylococcus sp.
The sensitivity of these organisms allows amoxicillin to also be effective in treating many common types of infections including upper and lower respiratory infections.
Other uses include skin tissue infections, otitis media, and urinary tract infections. Sign up for Cephalexin price alerts and find out when the price changes! Both cephalexin and amoxicillin have commonly been used off-label for endocarditis prophylaxis. Patients with congenital heart defects or prosthetic heart valves are at an increased risk of developing an infection in the lining of their heart after dental procedures.
Prophylactic doses of antibiotics such as amoxicillin and cephalexin given prior to these procedures have been shown to decrease the risk of such infections. The effectiveness of cephalexin or amoxicillin will vary with each bacteria type and each patient. With any sensitive bacteria, each drug may be effective so long as it is dosed appropriately at the correct intervals.
The effectiveness of beta-lactam antibiotics are dependent upon the amount of time that free, non-protein bound drug is above the minimum inhibitory concentration MIC of the bacteria. You should not use this medicine if you are allergic to cephalexin or any other cephalosporin antibiotic cefdinir, cefadroxil, cefoxitin, cefprozil, ceftriaxone, cefuroxime, Omnicef, and others.
The liquid form of cephalexin may contain sugar. This may affect you if you have diabetes. Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection.
If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. Use Cephalexin Keflex exactly as directed on the label, or as prescribed by your doctor.
Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Measure liquid medicine carefully.
0コメント